Evolutionary consequences of intra-patient phage predation on microbial populations

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Evolutionary consequences of intra-patient phage predation on microbial populations

The impact of phage predation on bacterial pathogens in the context of human disease is not currently appreciated. Here, we show that predatory interactions of a phage with an important environmentally transmitted pathogen, Vibrio cholerae, can modulate the evolutionary trajectory of this pathogen during the natural course of infection within individual patients. We analyzed geographically and ...

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ژورنال

عنوان ژورنال: eLife

سال: 2014

ISSN: 2050-084X

DOI: 10.7554/elife.03497